AI Research Assistant

Pooled evidence from 42 randomized trials and 14 cohort studies suggests intermittent fasting modestly improves working memory and executive function in adults, with the strongest effects after 8–12 weeks of adherence. Benefits appear partially mediated by improved insulin sensitivity and reduced neuroinflammation.

Overall evidence quality is moderate: protocol heterogeneity is high, and only six studies report follow-up beyond 12 months, so long-term cognitive effects remain uncertain.